Dice, Camera, Action frequently features guest stars, players who frequently portray important NPCs from the published adventures. The guest stars are listed in order of chronological appearance.
| Guest Star | Character | Episodes |
|---|---|---|
| Chris Trott | Falkon | 4, 5, 21 |
| Erika Ishii | Dee | 6, 7, 24, 25 |
| Mark Hulmes | Ezmerelda | 12, 13, 22 |
| Aram Vartian | Emil | 19, 33 |
| Liisa Lee | Arabelle | 26, 27 |
| Sam Witwer | Mordenkainen | 29, 55 |
| Satine Phoenix | Lafaria | 35 |
| Joe Hills | Harshnag | 39, 40 |
| Sam Sykes | Kozin Xorlarrin | 47, 48, 49 |
| Allie Gonino | Lilith | 51 |
| Dani Hartel | Xandala | 59, 60, 61, 62 |
| Geoff Robinson | Chumba | 64 |
| Ross O'Donovan | Wumba | 65, 66, 70 |
| Patrick Rothfuss | Kerrek | 69 |
| Matthew Lillard | Bag of Nails | 74, 75, 76 |
| Rachel Seeley | Miranda | 77, 78, 79, 80, 81, 82, 83, 84 |
| Jerry Holkins | Omin Dran | 90 |
